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Mendelian Randomization Analysis in Observational Epidemiology

Mendelian randomization (MR) in epidemiology is the use of genetic variants as instrumental variables (IVs) in non-experimental design to make causality of a modifiable exposure on an outcome or disease. It assesses the causal effect between risk factor and a clinical outcome. The main reason to app...

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Detalles Bibliográficos
Autores principales: Lee, Kwan, Lim, Chi-Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Lipidology and Atherosclerosis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379124/
https://www.ncbi.nlm.nih.gov/pubmed/32821701
http://dx.doi.org/10.12997/jla.2019.8.2.67