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Dynorphinergic system alterations in the corticostriatal circuitry of neuropathic mice support its role in the negative affective component of pain

The dynorphinergic system is involved in pain transmission at spinal level, where dynorphin exerts antinociceptive or pronociceptive effects, based on its opioid or non‐opioid actions. Surprisingly, little evidence is currently available concerning the supraspinal role of the dynorphinergic system i...

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Detalles Bibliográficos
Autores principales: Palmisano, M., Caputi, F. F., Mercatelli, D., Romualdi, P., Candeletti, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379183/
https://www.ncbi.nlm.nih.gov/pubmed/29430855
http://dx.doi.org/10.1111/gbb.12467