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Species‐specific inhibition of capripoxvirus replication by host antiviral protein kinase R

The role of interferon (IFN)‐induced protein kinase R (PKR) in capripoxvirus (CaPV)‐infected cells remains unknown. In this study, we show that CaPV infection triggered PKR and eukaryotic translation initiation factor 2 alpha (eIF2α) protein phosphorylation in a dose‐dependent manner, and that this...

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Detalles Bibliográficos
Autores principales: Zhao, Zhixun, Zhu, Xueliang, Wu, Na, Qin, Xiaodong, Huang, Caiyun, Wu, Guohua, Zhang, Qiang, Zhang, Zhidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379242/
https://www.ncbi.nlm.nih.gov/pubmed/30381842
http://dx.doi.org/10.1111/nyas.13976