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Predicting the Acute Liver Toxicity of Aflatoxin B1 in Rats and Humans by an In Vitro–In Silico Testing Strategy

SCOPE: High‐level exposure to aflatoxin B1 (AFB1) is known to cause acute liver damage and fatality in animals and humans. The intakes actually causing this acute toxicity have so far been estimated based on AFB1 levels in contaminated foods or biomarkers in serum. The aim of the present study is to...

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Detalles Bibliográficos
Autores principales: Gilbert‐Sandoval, Ixchel, Wesseling, Sebastiaan, Rietjens, Ivonne M. C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379280/
https://www.ncbi.nlm.nih.gov/pubmed/32421213
http://dx.doi.org/10.1002/mnfr.202000063