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Differential escape of HCV from CD8(+) T cell selection pressure between China and Germany depends on the presenting HLA class I molecule

Adaptation of hepatitis C virus (HCV) to CD8(+) T cell selection pressure is well described; however, it is unclear if HCV differentially adapts in different populations. Here, we studied HLA class I‐associated viral sequence polymorphisms in HCV 1b isolates in a Chinese population and compared vira...

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Detalles Bibliográficos
Autores principales: Xia, Youchen, Pan, Wen, Ke, Xiaoyu, Skibbe, Kathrin, Walker, Andreas, Hoffmann, Daniel, Lu, Yinping, Yang, Xuecheng, Feng, Xuemei, Tong, Qiaoxia, Timm, Jörg, Yang, Dongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379502/
https://www.ncbi.nlm.nih.gov/pubmed/30260541
http://dx.doi.org/10.1111/jvh.13011