Chloroquine Triggers Cell Death and Inhibits PARPs in Cell Models of Aggressive Hepatoblastoma

Background: Hepatoblastoma (HB) is the most common pediatric liver malignancy. Despite advances in chemotherapeutic regimens and surgical techniques, the survival of patients with advanced HB remains poor, underscoring the need for new therapeutic approaches. Chloroquine (CQ), a drug used to treat m...

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Detalles Bibliográficos
Autores principales: Eloranta, Katja, Cairo, Stefano, Liljeström, Emmi, Soini, Tea, Kyrönlahti, Antti, Judde, Jean-Gabriel, Wilson, David B., Heikinheimo, Markku, Pihlajoki, Marjut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379510/
https://www.ncbi.nlm.nih.gov/pubmed/32766148
http://dx.doi.org/10.3389/fonc.2020.01138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379510/
https://www.ncbi.nlm.nih.gov/pubmed/32766148
http://dx.doi.org/10.3389/fonc.2020.01138

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