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Novel immediate/sustained‐release formulation of acetaminophen‐ibuprofen combination (Paxerol®) for severe nocturia associated with overactive bladder: A multi‐center, randomized, double blinded, placebo‐controlled, 4‐arm trial

AIM: To determine short‐term efficacy and safety of Paxerol®, novel immediate:sustained (50%:50%) release tablets containing 325 mg acetaminophen and 150 mg ibuprofen per tablet. METHODS: One of three dose levels, corresponding to the amounts in 1, 2, and 3 tablets, of Paxerol and placebo were admin...

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Detalles Bibliográficos
Autores principales: Lee, King C., Rauscher, Frank, Kaminesky, Jed, Ryndin, Igor, Xie, Lei, Zhao, Yunzhu, Khusid, Johnathan A., Weiss, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379560/
https://www.ncbi.nlm.nih.gov/pubmed/30592553
http://dx.doi.org/10.1002/nau.23910