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An Agent‐Based Model for Pathogen Persistence and Cross‐Contamination Dynamics in a Food Facility
We used an agent‐based modeling (ABM) framework and developed a mathematical model to explain the complex dynamics of microbial persistence and spread within a food facility and to aid risk managers in identifying effective mitigation options. The model explicitly considered personal hygiene practic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379630/ https://www.ncbi.nlm.nih.gov/pubmed/30321463 http://dx.doi.org/10.1111/risa.13215 |
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author | Mokhtari, Amir Van Doren, Jane M. |
author_facet | Mokhtari, Amir Van Doren, Jane M. |
author_sort | Mokhtari, Amir |
collection | PubMed |
description | We used an agent‐based modeling (ABM) framework and developed a mathematical model to explain the complex dynamics of microbial persistence and spread within a food facility and to aid risk managers in identifying effective mitigation options. The model explicitly considered personal hygiene practices by food handlers as well as their activities and simulated a spatially explicit dynamic system representing complex interaction patterns among food handlers, facility environment, and foods. To demonstrate the utility of the model in a decision‐making context, we created a hypothetical case study and used it to compare different risk mitigation strategies for reducing contamination and spread of Listeria monocytogenes in a food facility. Model results indicated that areas with no direct contact with foods (e.g., loading dock and restroom) can serve as contamination niches and recontaminate areas that have direct contact with food products. Furthermore, food handlers’ behaviors, including, for example, hygiene and sanitation practices, can impact the persistence of microbial contamination in the facility environment and the spread of contamination to prepared foods. Using this case study, we also demonstrated benefits of an ABM framework for addressing food safety in a complex system in which emergent system‐level responses are predicted using a bottom‐up approach that observes individual agents (e.g., food handlers) and their behaviors. Our model can be applied to a wide variety of pathogens, food commodities, and activity patterns to evaluate efficacy of food‐safety management practices and quantify contamination reductions associated with proposed mitigation strategies in food facilities. |
format | Online Article Text |
id | pubmed-7379630 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73796302020-07-24 An Agent‐Based Model for Pathogen Persistence and Cross‐Contamination Dynamics in a Food Facility Mokhtari, Amir Van Doren, Jane M. Risk Anal Original Research Articles We used an agent‐based modeling (ABM) framework and developed a mathematical model to explain the complex dynamics of microbial persistence and spread within a food facility and to aid risk managers in identifying effective mitigation options. The model explicitly considered personal hygiene practices by food handlers as well as their activities and simulated a spatially explicit dynamic system representing complex interaction patterns among food handlers, facility environment, and foods. To demonstrate the utility of the model in a decision‐making context, we created a hypothetical case study and used it to compare different risk mitigation strategies for reducing contamination and spread of Listeria monocytogenes in a food facility. Model results indicated that areas with no direct contact with foods (e.g., loading dock and restroom) can serve as contamination niches and recontaminate areas that have direct contact with food products. Furthermore, food handlers’ behaviors, including, for example, hygiene and sanitation practices, can impact the persistence of microbial contamination in the facility environment and the spread of contamination to prepared foods. Using this case study, we also demonstrated benefits of an ABM framework for addressing food safety in a complex system in which emergent system‐level responses are predicted using a bottom‐up approach that observes individual agents (e.g., food handlers) and their behaviors. Our model can be applied to a wide variety of pathogens, food commodities, and activity patterns to evaluate efficacy of food‐safety management practices and quantify contamination reductions associated with proposed mitigation strategies in food facilities. John Wiley and Sons Inc. 2018-10-15 2019-05 /pmc/articles/PMC7379630/ /pubmed/30321463 http://dx.doi.org/10.1111/risa.13215 Text en Published 2018. This article is a U.S. Government work and is in the public domain in the USA. Risk Analysis published by Wiley Periodicals, Inc. on behalf of Society for Risk Analysis. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Research Articles Mokhtari, Amir Van Doren, Jane M. An Agent‐Based Model for Pathogen Persistence and Cross‐Contamination Dynamics in a Food Facility |
title | An Agent‐Based Model for Pathogen Persistence and Cross‐Contamination Dynamics in a Food Facility |
title_full | An Agent‐Based Model for Pathogen Persistence and Cross‐Contamination Dynamics in a Food Facility |
title_fullStr | An Agent‐Based Model for Pathogen Persistence and Cross‐Contamination Dynamics in a Food Facility |
title_full_unstemmed | An Agent‐Based Model for Pathogen Persistence and Cross‐Contamination Dynamics in a Food Facility |
title_short | An Agent‐Based Model for Pathogen Persistence and Cross‐Contamination Dynamics in a Food Facility |
title_sort | agent‐based model for pathogen persistence and cross‐contamination dynamics in a food facility |
topic | Original Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379630/ https://www.ncbi.nlm.nih.gov/pubmed/30321463 http://dx.doi.org/10.1111/risa.13215 |
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