Role of Proton-Coupled Monocarboxylate Transporters in Cancer: From Metabolic Crosstalk to Therapeutic Potential

Proton-coupled monocarboxylate transporters (MCTs), representing the first four isoforms of the SLC16A gene family, mainly participate in the transport of lactate, pyruvate, and other monocarboxylates. Cancer cells exhibit a metabolic shift from oxidative metabolism to an enhanced glycolytic phenoty...

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Detalles Bibliográficos
Autores principales: Sun, Xiangyu, Wang, Mozhi, Wang, Mengshen, Yao, Litong, Li, Xinyan, Dong, Haoran, Li, Meng, Sun, Tie, Liu, Xing, Liu, Yang, Xu, Yingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379837/
https://www.ncbi.nlm.nih.gov/pubmed/32766253
http://dx.doi.org/10.3389/fcell.2020.00651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379837/
https://www.ncbi.nlm.nih.gov/pubmed/32766253
http://dx.doi.org/10.3389/fcell.2020.00651

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