Acute Low Dose of Trazodone Recovers Glutamate Release Efficiency and mGlu2/3 Autoreceptor Impairments in the Spinal Cord of Rats Suffering From Chronic Sciatic Ligation

We investigated whether chronic sciatic ligation modifies the glutamate release in spinal cord nerve endings (synaptosomes) as well as the expression and the function of presynaptic release-regulating mGlu2/3 autoreceptors and 5-HT(2A) heteroreceptors in these particles. Synaptosomes were from the s...

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Detalles Bibliográficos
Autores principales: Cisani, Francesca, Roggeri, Alessandra, Olivero, Guendalina, Garrone, Beatrice, Tongiani, Serena, Di Giorgio, Francesco Paolo, Pittaluga, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379891/
https://www.ncbi.nlm.nih.gov/pubmed/32765286
http://dx.doi.org/10.3389/fphar.2020.01108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379891/
https://www.ncbi.nlm.nih.gov/pubmed/32765286
http://dx.doi.org/10.3389/fphar.2020.01108

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