Cargando…

Acute Low Dose of Trazodone Recovers Glutamate Release Efficiency and mGlu2/3 Autoreceptor Impairments in the Spinal Cord of Rats Suffering From Chronic Sciatic Ligation

We investigated whether chronic sciatic ligation modifies the glutamate release in spinal cord nerve endings (synaptosomes) as well as the expression and the function of presynaptic release-regulating mGlu2/3 autoreceptors and 5-HT(2A) heteroreceptors in these particles. Synaptosomes were from the s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cisani, Francesca, Roggeri, Alessandra, Olivero, Guendalina, Garrone, Beatrice, Tongiani, Serena, Di Giorgio, Francesco Paolo, Pittaluga, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379891/ https://www.ncbi.nlm.nih.gov/pubmed/32765286 http://dx.doi.org/10.3389/fphar.2020.01108

Ejemplares similares

Presynaptic 5-HT(2A)-mGlu2/3 Receptor–Receptor Crosstalk in the Prefrontal Cortex: Metamodulation of Glutamate Exocytosis
por: Taddeucci, Alice, et al.
Publicado: (2022)

Presynaptic Release-regulating Metabotropic Glutamate Receptors: An Update
por: Olivero, Guendalina, et al.
Publicado: (2020)

Presynaptic mGlu1 Receptors Control GABA(B) Receptors in an Antagonist-Like Manner in Mouse Cortical GABAergic and Glutamatergic Nerve Endings
por: Vergassola, Matteo, et al.
Publicado: (2018)

Presynaptic Release-Regulating Alpha2 Autoreceptors: Potential Molecular Target for Ellagic Acid Nutraceutical Properties
por: Romeo, Isabella, et al.
Publicado: (2021)

Structural insights into dimerization and activation of the mGlu2–mGlu3 and mGlu2–mGlu4 heterodimers
por: Wang, Xinwei, et al.
Publicado: (2023)

mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists
por: Zammataro, Magda, et al.
Publicado: (2011)

Anti-NMDA and Anti-AMPA Receptor Antibodies in Central Disorders: Preclinical Approaches to Assess Their Pathological Role and Translatability to Clinic
por: Olivero, Guendalina, et al.
Publicado: (2023)

Antibodies Against the NH(2)-Terminus of the GluA Subunits Affect the AMPA-Evoked Releasing Activity: The Role of Complement
por: Cisani, Francesca, et al.
Publicado: (2021)

Presynaptic Release-Regulating mGlu1 Receptors in Central Nervous System
por: Pittaluga, Anna
Publicado: (2016)

Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice
por: Lane, Tracy A, et al.
Publicado: (2013)

Somatostatin, a Presynaptic Modulator of Glutamatergic Signal in the Central Nervous System
por: Pittaluga, Anna, et al.
Publicado: (2021)

Synergistic interaction between trazodone and gabapentin in rodent models of neuropathic pain
por: Garrone, Beatrice, et al.
Publicado: (2021)

Place field stability requires the metabotropic glutamate receptor, mGlu5
por: Zhang, Sijie, et al.
Publicado: (2014)

Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720
por: Roggeri, Alessandra, et al.
Publicado: (2023)

Estimation of an Appropriate Dose of Trazodone for Pediatric Insomnia and the Potential for a Trazodone–Atomoxetine Interaction
por: Oggianu, Laura, et al.
Publicado: (2020)

An Appraisal of the Influence of the Metabotropic Glutamate 5 (mGlu5) Receptor on Sociability and Anxiety
por: Ramos-Prats, Arnau, et al.
Publicado: (2019)

Allosteric Modulators for mGlu Receptors
por: Gasparini, F, et al.
Publicado: (2007)

Deletion of Metabotropic Glutamate Receptors 2 and 3 (mGlu2 & mGlu3) in Mice Disrupts Sleep and Wheel-Running Activity, and Increases the Sensitivity of the Circadian System to Light
por: Pritchett, David, et al.
Publicado: (2015)

A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding
por: García-Bea, Aintzane, et al.
Publicado: (2017)

Healthy Properties of a New Formulation of Pomegranate-Peel Extract in Mice Suffering from Experimental Autoimmune Encephalomyelitis
por: Vallarino, Giulia, et al.
Publicado: (2022)

Phosphorylation and regulation of group II metabotropic glutamate receptors (mGlu2/3) in neurons
por: Mao, Li-Min, et al.
Publicado: (2022)

Neuroinflammation in Aged Brain: Impact of the Oral Administration of Ellagic Acid Microdispersion
por: Boggia, Raffaella, et al.
Publicado: (2020)

Tetrahydronaphthyridine and Dihydronaphthyridinone Ethers As Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 5 (mGlu(5))
por: Turlington, Mark, et al.
Publicado: (2014)

Altered Short-Term Synaptic Plasticity in Mice Lacking the Metabotropic Glutamate Receptor mGlu7
por: Bushell, Trevor J., et al.
Publicado: (2002)

Protein Networks Associated with Native Metabotropic Glutamate 1 Receptors (mGlu(1)) in the Mouse Cerebellum
por: Mansouri, Mahnaz, et al.
Publicado: (2023)

Emotional Impairment and Persistent Upregulation of mGlu(5) Receptor following Morphine Abstinence: Implications of an mGlu(5)-MOPr Interaction
por: Zanos, Panos, et al.
Publicado: (2016)

mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors
por: Notartomaso, Serena, et al.
Publicado: (2018)

The Metabotropic Glutamate Receptor, mGlu5, Is Required for Extinction Learning That Occurs in the Absence of a Context Change
por: André, Marion Agnes Emma, et al.
Publicado: (2015)

Targeting mGlu5 Metabotropic Glutamate Receptors in the Treatment of Cognitive Dysfunction in a Mouse Model of Phenylketonuria
por: Nardecchia, Francesca, et al.
Publicado: (2018)

Glutamate Metabotropic Receptor Type 3 (mGlu3) Localization in the Rat Prelimbic Medial Prefrontal Cortex
por: Woo, Elizabeth, et al.
Publicado: (2022)

Fractionation of Spatial Memory in GRM2/3 (mGlu2/mGlu3) Double Knockout Mice Reveals a Role for Group II Metabotropic Glutamate Receptors at the Interface Between Arousal and Cognition
por: Lyon, Louisa, et al.
Publicado: (2011)

mGlu5 Receptor Functional Interactions and Addiction
por: Brown, Robyn M., et al.
Publicado: (2012)

mGlu(5) Positive Allosteric Modulators Facilitate Long-Term Potentiation via Disinhibition Mediated by mGlu(5)-Endocannabinoid Signaling
por: Xiang, Zixiu, et al.
Publicado: (2019)

Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia
por: Fazio, Francesco, et al.
Publicado: (2015)

Genetic Deletion of mGlu3 Metabotropic Glutamate Receptors Amplifies Ischemic Brain Damage and Associated Neuroinflammation in Mice
por: Mastroiacovo, Federica, et al.
Publicado: (2021)

mGlu3 Metabotropic Glutamate Receptors as a Target for the Treatment of Absence Epilepsy: Preclinical and Human Genetics Data
por: Celli, Roberta, et al.
Publicado: (2023)

Neurobiological Insights from mGlu Receptor Allosteric Modulation
por: O’Brien, Daniel E, et al.
Publicado: (2015)

Exploring the Activation Mechanism of the mGlu5 Transmembrane Domain
por: Lans, Isaias, et al.
Publicado: (2020)

Regulation and functional consequences of mGlu(4) RNA editing
por: Hofmann, Christopher S., et al.
Publicado: (2021)

The Depolarization-Evoked, Ca(2+)-Dependent Release of Exosomes From Mouse Cortical Nerve Endings: New Insights Into Synaptic Transmission
por: Olivero, Guendalina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_h296raads0irt9u47q2j8d90q7