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The T Cell Receptor Repertoire in Neuropsychiatric Systemic Lupus Erythematosus
Objective: In systemic lupus erythematosus (SLE), widespread T cell infiltration into target organs contributes to inflammation and organ damage. Autoreactive T cells become aberrantly activated in this disease due to dysfunctional T cell receptor signaling that lowers the activation threshold. Char...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379895/ https://www.ncbi.nlm.nih.gov/pubmed/32765512 http://dx.doi.org/10.3389/fimmu.2020.01476 |