The T Cell Receptor Repertoire in Neuropsychiatric Systemic Lupus Erythematosus

Objective: In systemic lupus erythematosus (SLE), widespread T cell infiltration into target organs contributes to inflammation and organ damage. Autoreactive T cells become aberrantly activated in this disease due to dysfunctional T cell receptor signaling that lowers the activation threshold. Char...

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Detalles Bibliográficos
Autores principales: Moore, Erica, Huang, Michelle W., Jain, Shweta, Chalmers, Samantha A., Macian, Fernando, Putterman, Chaim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379895/
https://www.ncbi.nlm.nih.gov/pubmed/32765512
http://dx.doi.org/10.3389/fimmu.2020.01476

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