Elucidation of Mechanisms of Topotecan-Induced Cell Death in Human Breast MCF-7 Cancer Cells by Gene Expression Analysis

Topotecan is a clinically active anticancer agent for the management of various human tumors. While the principal mechanism of tumor cell killing by topotecan is due to its interactions with topoisomerase I and formation of DNA double-strand breaks, recent studies suggest that mechanisms involving g...

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Detalles Bibliográficos
Autores principales: Sinha, Birandra K., Tokar, Erik J., Bushel, Pierre R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379903/
https://www.ncbi.nlm.nih.gov/pubmed/32765594
http://dx.doi.org/10.3389/fgene.2020.00775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379903/
https://www.ncbi.nlm.nih.gov/pubmed/32765594
http://dx.doi.org/10.3389/fgene.2020.00775

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