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TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF‐κB signaling

This study aimed to investigate the effects of triggering receptor expressed on myeloid cell‐2 (TREM2) on the production of pro‐inflammatory mediators and cytokines induced by lipopolysaccharide (LPS) in BV2 microglia. TREM2 expression or TREM2‐specific siRNA were used to induce TREM2 overexpression...

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Detalles Bibliográficos
Autores principales: Li, Caixia, Zhao, Bing, Lin, Caizhao, Gong, Zhiping, An, Xiaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379930/
https://www.ncbi.nlm.nih.gov/pubmed/29663649
http://dx.doi.org/10.1002/cbin.10975