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Endotracheal intubation results in acute tracheal damage induced by mtDNA/TLR9/NF‐κB activity

Tracheitis secondary to placement of an endotracheal tube (ETT) is characterized by neutrophil accumulation in the tracheal lumen, which is generally associated with epithelial damage. Mitochondrial DNA (mtDNA), has been implicated in systemic inflammation and organ dysfunction following trauma; how...

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Detalles Bibliográficos
Autores principales: Puyo, Carlos A., Earhart, Alexander, Staten, Nicholas, Prince, Oliver A., Haug, Colleen, Kollef, Marin, Awad, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379990/
https://www.ncbi.nlm.nih.gov/pubmed/30548974
http://dx.doi.org/10.1002/JLB.5A0718-254RR