Ubiquitin‐independent, Proteasome‐mediated targeted degradation of KRAS in pancreatic adenocarcinoma cells using an engineered ornithine decarboxylase/antizyme system

The oncogene KRAS not only promotes the tumorigenesis of pancreatic cancers but also is required for the malignant progression and metastasis of these cancers. Many methods have been explored to influence the malignant biological behavior of these cancers by targeting mutant KRAS. The ornithine deca...

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Detalles Bibliográficos
Autores principales: Ma, Yihui, Xu, Jingjing, Huang, Pei, Bai, Xue, Gao, Hanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379993/
https://www.ncbi.nlm.nih.gov/pubmed/30347501
http://dx.doi.org/10.1002/iub.1945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379993/
https://www.ncbi.nlm.nih.gov/pubmed/30347501
http://dx.doi.org/10.1002/iub.1945

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