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Identification of high-affinity inhibitors of SARS-CoV-2 main protease: Towards the development of effective COVID-19 therapy

Coronavirus disease 2019 (COVID-19) is an infectious disease, caused by a newly emerged highly pathogenic virus called novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Targeting the main protease (M(pro), 3CL(pro)) of SARS-CoV-2 is an appealing approach for drug development becaus...

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Detalles Bibliográficos
Autores principales: Mohammad, Taj, Shamsi, Anas, Anwar, Saleha, Umair, Mohd., Hussain, Afzal, Rehman, Md. Tabish, AlAjmi, Mohamed F., Islam, Asimul, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380256/
https://www.ncbi.nlm.nih.gov/pubmed/32717346
http://dx.doi.org/10.1016/j.virusres.2020.198102