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Ethyl pyruvate inhibits glioblastoma cells migration and invasion through modulation of NF-κB and ERK-mediated EMT

BACKGROUND: Glioblastoma is a grade IV glioma with the highest degree of malignancy and extremely high incidence. Because of the poor therapeutic effect of surgery and radiochemotherapy, glioblastoma has a high recurrence rate and lethality, and is one of the most challenging tumors in the field of...

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Detalles Bibliográficos
Autores principales: Huang, Qing, Fu, Yongming, Zhang, Shan, Zhang, Youxiang, Chen, Simin, Zhang, Zuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380274/
https://www.ncbi.nlm.nih.gov/pubmed/32742812
http://dx.doi.org/10.7717/peerj.9559