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Tubuloglomerular Feedback in Renal Glucosuria: Mimicking Long-term SGLT-2 Inhibitor Therapy

A patient with renal glucosuria due to a congenital knock-out of the sodium-glucose cotransporter 2 (SGLT-2) protein because of a compound heterozygous mutation in the SLC5A2 gene may provide a natural model mimicking the effects of long-term SGLT-2 inhibitor therapy, which has been shown to exert k...

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Detalles Bibliográficos
Autores principales: Neuwirt, Hannes, Burtscher, Andrea, Cherney, David, Mayer, Gert, Ebenbichler, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380363/
https://www.ncbi.nlm.nih.gov/pubmed/32734228
http://dx.doi.org/10.1016/j.xkme.2019.09.006