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RocA Regulates Phosphatase Activity of Virulence Sensor CovS of Group A Streptococcus in Growth Phase- and pH-Dependent Manners

The control of the virulence response regulator and sensor (CovR-CovS) two-component regulatory system in group A Streptococcus (GAS) strains regulates more than 15% of gene expression and has critical roles in invasive GAS infection. The membrane-embedded CovS has kinase and phosphatase activities,...

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Detalles Bibliográficos
Autores principales: Chiang-Ni, Chuan, Chiou, He-Jing, Tseng, Huei-Chuan, Hsu, Chih-Yun, Chiu, Cheng-Hsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380576/
https://www.ncbi.nlm.nih.gov/pubmed/32434842
http://dx.doi.org/10.1128/mSphere.00361-20