Philanthotoxin-343 attenuates retinal and optic nerve injury, and protects visual function in rats with N-methyl-D-aspartate-induced excitotoxicity

Retinal ganglion cell (RGC) loss and optic neuropathy, both hallmarks of glaucoma, have been shown to involve N-methyl-D-aspartate receptor (NMDAR)-mediated excitotoxicity. This study investigated the neuroprotective effects of Philanthotoxin (PhTX)-343 in NMDA-induced retinal injury to alleviate en...

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Detalles Bibliográficos
Autores principales: Fazel, Muhammad Fattah, Abu, Izuddin Fahmy, Mohamad, Mohamad Haiqal Nizar, Agarwal, Renu, Iezhitsa, Igor, Bakar, Nor Salmah, Juliana, Norsham, Mellor, Ian R., Franzyk, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380593/
https://www.ncbi.nlm.nih.gov/pubmed/32706792
http://dx.doi.org/10.1371/journal.pone.0236450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380593/
https://www.ncbi.nlm.nih.gov/pubmed/32706792
http://dx.doi.org/10.1371/journal.pone.0236450

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