Cargando…
Philanthotoxin-343 attenuates retinal and optic nerve injury, and protects visual function in rats with N-methyl-D-aspartate-induced excitotoxicity
Retinal ganglion cell (RGC) loss and optic neuropathy, both hallmarks of glaucoma, have been shown to involve N-methyl-D-aspartate receptor (NMDAR)-mediated excitotoxicity. This study investigated the neuroprotective effects of Philanthotoxin (PhTX)-343 in NMDA-induced retinal injury to alleviate en...
Autores principales: | Fazel, Muhammad Fattah, Abu, Izuddin Fahmy, Mohamad, Mohamad Haiqal Nizar, Agarwal, Renu, Iezhitsa, Igor, Bakar, Nor Salmah, Juliana, Norsham, Mellor, Ian R., Franzyk, Henrik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380593/ https://www.ncbi.nlm.nih.gov/pubmed/32706792 http://dx.doi.org/10.1371/journal.pone.0236450 |
Ejemplares similares
-
Neuroprotection Against NMDA-Induced Retinal Damage by Philanthotoxin-343 Involves Reduced Nitrosative Stress
por: Mohamad, Mohamad Haiqal Nizar, et al.
Publicado: (2021) -
Readiness of Bystander Cardiopulmonary Resuscitation (BCPR) during the COVID-19 Pandemic: A Review
por: Fazel, Muhammad Fattah, et al.
Publicado: (2022) -
Block of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition
por: Kachel, Hamid S., et al.
Publicado: (2016) -
The Effects of Structural Alterations in the Polyamine and Amino Acid Moieties of Philanthotoxins on Nicotinic Acetylcholine Receptor Inhibition in the Locust, Schistocerca gregaria
por: Luck, Victoria L., et al.
Publicado: (2021) -
Tocotrienol-rich fraction reduces retinal inflammation and angiogenesis in rats with streptozotocin-induced diabetes
por: Sadikan, Muhammad Zulfiqah, et al.
Publicado: (2023)