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Development of a brain-permeable peptide nanofiber that prevents aggregation of Alzheimer pathogenic proteins
Alzheimer's disease (AD) is proposed to be induced by abnormal aggregation of amyloidβ in the brain. Here, we designed a brain-permeable peptide nanofiber drug from a fragment of heat shock protein to suppress aggregation of the pathogenic proteins. To facilitate delivery of the nanofiber into...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380640/ https://www.ncbi.nlm.nih.gov/pubmed/32706773 http://dx.doi.org/10.1371/journal.pone.0235979 |