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Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury
In the context of human disease, the mechanisms whereby transcription factors reprogram gene expression in reparative responses to injury are not well understood. We have studied the mechanisms of transcriptional reprogramming in disease using murine kidney podocytes as a model for tissue injury. Po...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380960/ https://www.ncbi.nlm.nih.gov/pubmed/32754639 http://dx.doi.org/10.1126/sciadv.abb5460 |