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Increased Osteoblastic Cxcl9 Contributes to the Uncoupled Bone Formation and Resorption in Postmenopausal Osteoporosis

INTRODUCTION: Estrogen deficiency leads to bone loss in postmenopausal osteoporosis, because bone formation, albeit enhanced, fails to keep pace with the stimulated osteoclastic bone resorption. The mechanism driving this uncoupling is central to the pathogenesis of postmenopausal osteoporosis, whic...

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Detalles Bibliográficos
Autores principales: Liu, Zezheng, Liang, Wenquan, Kang, Dawei, Chen, Qingjing, Ouyang, Zhicong, Yan, Huibo, Huang, Bin, Jin, Dadi, Chen, Yinkui, Li, Qingchu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381095/
https://www.ncbi.nlm.nih.gov/pubmed/32764906
http://dx.doi.org/10.2147/CIA.S254885