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Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency

Retinitis Pigmentosa (RP) is a group of inherited retinal diseases characterized by progressive loss of rod followed by cone photoreceptors. An especially early onset form of RP with blindness in teenage years is caused by mutations in mertk, the gene encoding the clearance phagocytosis receptor Mer...

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Detalles Bibliográficos
Autores principales: Lew, Deborah S., Mazzoni, Francesca, Finnemann, Silvia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381113/
https://www.ncbi.nlm.nih.gov/pubmed/32765507
http://dx.doi.org/10.3389/fimmu.2020.01463