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Progress in LRRK2-Associated Parkinson’s Disease Animal Models

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most frequent cause of familial Parkinson’s disease (PD). Several genetic manipulations of the LRRK2 gene have been developed in animal models such as rodents, Drosophila, Caenorhabditis elegans, and zebrafish. These models can help...

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Detalles Bibliográficos
Autores principales: Seegobin, Steven P., Heaton, George R., Liang, Dongxiao, Choi, Insup, Blanca Ramirez, Marian, Tang, Beisha, Yue, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381130/
https://www.ncbi.nlm.nih.gov/pubmed/32765209
http://dx.doi.org/10.3389/fnins.2020.00674