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Microglia Susceptibility to Free Bilirubin Is Age-Dependent

Increased concentrations of unconjugated bilirubin (UCB), namely its free fraction (Bf), in neonatal life may cause transient or definitive injury to neurons and glial cells. We demonstrated that UCB damages neurons and glial cells by compromising oligodendrocyte maturation and myelination, and by a...

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Detalles Bibliográficos
Autores principales: Vaz, Ana Rita, Falcão, Ana Sofia, Scarpa, Eleonora, Semproni, Carlotta, Brites, Dora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381152/
https://www.ncbi.nlm.nih.gov/pubmed/32765258
http://dx.doi.org/10.3389/fphar.2020.01012