Intravenous Injection of PHF-Tau Proteins From Alzheimer Brain Exacerbates Neuroinflammation, Amyloid Beta, and Tau Pathologies in 5XFAD Transgenic Mice

Alzheimer’s disease (AD) is characterized by the accumulation in the brain of intraneuronal aggregates of abnormally and hyperphosphorylated tau proteins and of extracellular deposits of amyloid-β surrounded by dystrophic neurites. Numerous experimental models have shown that tau pathology develops...

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Detalles Bibliográficos
Autores principales: Houben, Sarah, de Fisenne, Marie-Ange, Ando, Kunie, Vanden Dries, Virginie, Poncelet, Luc, Yilmaz, Zehra, Mansour, Salwa, De Decker, Robert, Brion, Jean-Pierre, Leroy, Karelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381181/
https://www.ncbi.nlm.nih.gov/pubmed/32765217
http://dx.doi.org/10.3389/fnmol.2020.00106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381181/
https://www.ncbi.nlm.nih.gov/pubmed/32765217
http://dx.doi.org/10.3389/fnmol.2020.00106

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