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A Probabilistic Approach to Explore Signal Execution Mechanisms With Limited Experimental Data

Mathematical models of biochemical reaction networks are central to the study of dynamic cellular processes and hypothesis generation that informs experimentation and validation. Unfortunately, model parameters are often not available and sparse experimental data leads to challenges in model calibra...

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Detalles Bibliográficos
Autores principales: Kochen, Michael A., Lopez, Carlos F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381302/
https://www.ncbi.nlm.nih.gov/pubmed/32754196
http://dx.doi.org/10.3389/fgene.2020.00686