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Synonymous Mutations of Porcine Igf1r Extracellular Domain Affect Differentiation and Mineralization in MC3T3-E1 Cells

Owing to the wide application of miniature pigs in biomedicine, the formation mechanism of its short stature must be elucidated. The insulin-like growth factor 1 receptor (IGF-1R), which receives signals through the extracellular domain (ECD) binding with ligands, is crucial in regulating cell growt...

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Detalles Bibliográficos
Autores principales: Wang, Chunli, Wang, Siyao, Liu, Songcai, Cheng, Yunyun, Geng, Hongwei, Yang, Rui, Feng, Tianqi, Lu, Guanhong, Sun, Xiaotong, Song, Jie, Hao, Linlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381325/
https://www.ncbi.nlm.nih.gov/pubmed/32754602
http://dx.doi.org/10.3389/fcell.2020.00623