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Changes in DNA 5-Hydroxymethylcytosine Levels and the Underlying Mechanism in Non-functioning Pituitary Adenomas

Epigenetic factors have been proven to contribute to pituitary adenoma formation. 5-hydroxymethylcytosine (5hmC), which is catalyzed by ten-eleven translocation 2 (TET2), is related to DNA demethylation. In order to explore the pathogenesis of non-functioning pituitary adenomas (NFPAs), we detected...

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Detalles Bibliográficos
Autores principales: Xu, Yiwen, Niu, Yamei, Deng, Kan, Pan, Hui, Feng, Feng, Gong, Fengying, Tong, Wei-Min, Chen, Shi, Lu, Lin, Wang, Renzhi, You, Hui, Yao, Yong, Zhu, Huijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381329/
https://www.ncbi.nlm.nih.gov/pubmed/32774324
http://dx.doi.org/10.3389/fendo.2020.00361