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Landscape of circulating tumour DNA in metastatic breast cancer

BACKGROUND: We describe the genomic landscape of circulating tumour DNA (ctDNA) across pathological subtypes of metastatic breast cancer. METHODS: 255 clinically annotated patients with ctDNA testing by Guardant360 were stratified into HR+, HER2+, and TNBC cohorts. Frequency and heterogeneity of alt...

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Detalles Bibliográficos
Autores principales: Davis, Andrew A., Jacob, Saya, Gerratana, Lorenzo, Shah, Ami N., Wehbe, Firas, Katam, Neelima, Zhang, Qiang, Flaum, Lisa, Siziopikou, Kalliopi P., Platanias, Leonidas C., Gradishar, William J., Behdad, Amir, Cristofanilli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381501/
https://www.ncbi.nlm.nih.gov/pubmed/32707446
http://dx.doi.org/10.1016/j.ebiom.2020.102914