Differential expression of tissue-restricted antigens among mTEC is associated with distinct autoreactive T cell fates

Medullary thymic epithelial cells (mTEC) contribute to the development of T cell tolerance by expressing and presenting tissue-restricted antigens (TRA), so that developing T cells can assess the self-reactivity of their antigen receptors prior to leaving the thymus. mTEC are a heterogeneous populat...

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Detalles Bibliográficos
Autores principales: Lebel, Marie-Ève, Coutelier, Marie, Galipeau, Maria, Kleinman, Claudia L., Moon, James J., Melichar, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381629/
https://www.ncbi.nlm.nih.gov/pubmed/32709894
http://dx.doi.org/10.1038/s41467-020-17544-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381629/
https://www.ncbi.nlm.nih.gov/pubmed/32709894
http://dx.doi.org/10.1038/s41467-020-17544-3

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