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Dendrimer-coated carbon nanotubes deliver dsRNA and increase the efficacy of gene knockdown in the red flour beetle Tribolium castaneum

In this study, the use of dendrimer-coated carbon nanotubes (CNTs) as a delivery vehicle for dsRNA was assessed in Tribolium castaneum. Exposure to low dosages of polyamidoamine dendrimer carbon nanotubes (PAMAM-CNTs) did not affect T. castaneum larval mortality. Expression of key apoptotic factors,...

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Detalles Bibliográficos
Autores principales: Edwards, Catriona H., Christie, Craig R., Masotti, Andrea, Celluzzi, Antonella, Caporali, Andrea, Campbell, Ewan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381663/
https://www.ncbi.nlm.nih.gov/pubmed/32709999
http://dx.doi.org/10.1038/s41598-020-69068-x