A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice

The Cre-loxP recombination system is a powerful tool for genetic manipulation. However, there are widely recognized limitations with chemically inducible Cre-loxP systems, and the UV and blue-light induced systems have phototoxicity and minimal capacity for deep tissue penetration. Here, we develop...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Jiali, Wang, Meiyan, Yang, Xueping, Yi, Chengwei, Jiang, Jian, Yu, Yuanhuan, Ye, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381682/
https://www.ncbi.nlm.nih.gov/pubmed/32709899
http://dx.doi.org/10.1038/s41467-020-17530-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381682/
https://www.ncbi.nlm.nih.gov/pubmed/32709899
http://dx.doi.org/10.1038/s41467-020-17530-9

Ejemplares similares