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Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons

Hippocampal Lewy body pathology (LBP) is associated with changes in neurotrophic factor signaling and neuronal energy metabolism. LBP progression is attributed to the aggregation of α-synuclein (α-Syn) and its cell-to-cell transmission via extracellular vehicles (EVs). We recently discovered an enha...

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Detalles Bibliográficos
Autores principales: Kumar, Rohit, Donakonda, Sainitin, Müller, Stephan A., Lichtenthaler, Stefan F., Bötzel, Kai, Höglinger, Günter U., Koeglsperger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381695/
https://www.ncbi.nlm.nih.gov/pubmed/32707433
http://dx.doi.org/10.1016/j.isci.2020.101349