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Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons
Hippocampal Lewy body pathology (LBP) is associated with changes in neurotrophic factor signaling and neuronal energy metabolism. LBP progression is attributed to the aggregation of α-synuclein (α-Syn) and its cell-to-cell transmission via extracellular vehicles (EVs). We recently discovered an enha...
Autores principales: | Kumar, Rohit, Donakonda, Sainitin, Müller, Stephan A., Lichtenthaler, Stefan F., Bötzel, Kai, Höglinger, Günter U., Koeglsperger, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381695/ https://www.ncbi.nlm.nih.gov/pubmed/32707433 http://dx.doi.org/10.1016/j.isci.2020.101349 |
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