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A new class of PentixaFor- and PentixaTher-based theranostic agents with enhanced CXCR4-targeting efficiency

Non-invasive PET imaging of CXCR4 expression in cancer and inflammation as well as CXCR4-targeted radioligand therapy (RLT) have recently found their way into clinical research by the development of the theranostic agents [(68)Ga]PentixaFor (cyclo(D-Tyr(1)-D-[NMe]Orn(2)(AMBS-[(68)Ga]DOTA)-Arg(3)-Nal...

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Detalles Bibliográficos
Autores principales: Osl, Theresa, Schmidt, Alexander, Schwaiger, Markus, Schottelius, Margret, Wester, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381729/
https://www.ncbi.nlm.nih.gov/pubmed/32724470
http://dx.doi.org/10.7150/thno.45537