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Modulation of the Astrocyte-Neuron Lactate Shuttle System contributes to Neuroprotective action of Fibroblast Growth Factor 21

A viewpoint considering Alzheimer's disease (AD) as “type 3 diabetes” emphasizes the pivotal role of dysfunctional brain energy metabolism in AD. The hormone fibroblast growth factor 21 (FGF21) is a crucial regulator in energy metabolism; however, our understanding of the therapeutic potential...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Wang, Yue, Chen, Su-Ting, Chen, Ying-Jie, Shen, Jie, Yao, Wen-Bing, Gao, Xiang-Dong, Chen, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381735/
https://www.ncbi.nlm.nih.gov/pubmed/32724479
http://dx.doi.org/10.7150/thno.44370