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STEAP4 Inhibits HIF-1α/PKM2 Signaling and Reduces High Glucose-Induced Apoptosis of Retinal Vascular Endothelial Cells

BACKGROUND: Diabetic retinopathy (DR) is a vascular lesion induced by high glucose. STEAP4 is an indispensable membrane protein, which is closely related to hyperglycemic-induced cell inflammation and injury, while STEPT4 has not been studied in hyperglycemic-induced retinal vascular endothelial cel...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Xu, Hui, Zhao, Hongyu, Jiang, Chunying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381765/
https://www.ncbi.nlm.nih.gov/pubmed/32765036
http://dx.doi.org/10.2147/DMSO.S251663