The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy

BACKGROUND AND PURPOSE: Autophagy is the main protective mechanism against aging in podocytes, which are terminally differentiated cells that have a very limited capacity for mitosis and self-renewal. Here, a streptozotocin-induced DN C57BL/6 mouse model was used to investigate the effects of puerar...

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Detalles Bibliográficos
Autores principales: Xu, Xiaohui, Chen, Biao, Huang, Qichun, Wu, Yani, Liang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381766/
https://www.ncbi.nlm.nih.gov/pubmed/32765037
http://dx.doi.org/10.2147/DMSO.S256457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381766/
https://www.ncbi.nlm.nih.gov/pubmed/32765037
http://dx.doi.org/10.2147/DMSO.S256457

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