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Combination of CpG Oligodeoxynucleotide and Anti-4-1BB Antibody in the Treatment of Multiple Hepatocellular Carcinoma in Mice

BACKGROUND: To investigate the effect of topical application of CpG oligodeoxynucleotide (CpG-ODN) combined with anti-4-1BB antibodies on mouse HCC multiple tumor-bearing models and the degree of improvement of anti-tumor immune response in mice. MATERIALS AND METHODS: We inoculated each BALB/c male...

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Detalles Bibliográficos
Autores principales: Ma, Shizhao, Yang, Xinying, Zhou, Huifang, Zhang, Chaoqun, Kang, Jiwen, Sun, Dianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381816/
https://www.ncbi.nlm.nih.gov/pubmed/32764990
http://dx.doi.org/10.2147/OTT.S260353