Synthesis, density functional theory study and in vitro antimicrobial evaluation of new benzimidazole Mannich bases

The tri-component synthesis of novel chiral benzimidazole Mannich bases, by reaction between benzimidazole, aqueous 30% formaldehyde and an amine, the biological evaluation and DFT studies of the new compounds are reported here. The (1)H-NMR, (13)C-NMR, FTIR spectra and elemental analysis confirm th...

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Detalles Bibliográficos
Autores principales: Marinescu, Maria, Cinteză, Ludmila Otilia, Marton, George Iuliu, Chifiriuc, Mariana-Carmen, Popa, Marcela, Stănculescu, Ioana, Zălaru, Christina-Marie, Stavarache, Cristina-Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382033/
https://www.ncbi.nlm.nih.gov/pubmed/32724899
http://dx.doi.org/10.1186/s13065-020-00697-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382033/
https://www.ncbi.nlm.nih.gov/pubmed/32724899
http://dx.doi.org/10.1186/s13065-020-00697-z

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