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Synthesis, density functional theory study and in vitro antimicrobial evaluation of new benzimidazole Mannich bases
The tri-component synthesis of novel chiral benzimidazole Mannich bases, by reaction between benzimidazole, aqueous 30% formaldehyde and an amine, the biological evaluation and DFT studies of the new compounds are reported here. The (1)H-NMR, (13)C-NMR, FTIR spectra and elemental analysis confirm th...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382033/ https://www.ncbi.nlm.nih.gov/pubmed/32724899 http://dx.doi.org/10.1186/s13065-020-00697-z |