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Towards an improved early diagnosis of neurodegenerative diseases: the emerging role of in vitro conversion assays for protein amyloids

Tissue accumulation of abnormal aggregates of amyloidogenic proteins such as prion protein, α-synuclein, and tau represents the hallmark of most common neurodegenerative disorders and precedes the onset of symptoms by years. As a consequence, the sensitive and specific detection of abnormal forms of...

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Detalles Bibliográficos
Autores principales: Candelise, Niccolò, Baiardi, Simone, Franceschini, Alessia, Rossi, Marcello, Parchi, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382043/
https://www.ncbi.nlm.nih.gov/pubmed/32711575
http://dx.doi.org/10.1186/s40478-020-00990-x