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Bayesian inference of reassortment networks reveals fitness benefits of reassortment in human influenza viruses

Reassortment is an important source of genetic diversity in segmented viruses and is the main source of novel pathogenic influenza viruses. Despite this, studying the reassortment process has been constrained by the lack of a coherent, model-based inference framework. Here, we introduce a coalescent...

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Detalles Bibliográficos
Autores principales: Müller, Nicola F., Stolz, Ugnė, Dudas, Gytis, Stadler, Tanja, Vaughan, Timothy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382287/
https://www.ncbi.nlm.nih.gov/pubmed/32631984
http://dx.doi.org/10.1073/pnas.1918304117