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Mismatch-tolerant, alignment-free sequence classification using multiple spaced seeds and multiindex Bloom filters

Alignment-free classification tools have enabled high-throughput processing of sequencing data in many bioinformatics analysis pipelines primarily due to their computational efficiency. Originally k-mer based, such tools often lack sensitivity when faced with sequencing errors and polymorphisms. In...

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Detalles Bibliográficos
Autores principales: Chu, Justin, Mohamadi, Hamid, Erhan, Emre, Tse, Jeffery, Chiu, Readman, Yeo, Sarah, Birol, Inanc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382288/
https://www.ncbi.nlm.nih.gov/pubmed/32641514
http://dx.doi.org/10.1073/pnas.1903436117