Stem cell lineage survival as a noisy competition for niche access

Understanding to what extent stem cell potential is a cell-intrinsic property or an emergent behavior coming from global tissue dynamics and geometry is a key outstanding question of systems and stem cell biology. Here, we propose a theory of stem cell dynamics as a stochastic competition for access...

Descripción completa

Detalles Bibliográficos
Autores principales: Corominas-Murtra, Bernat, Scheele, Colinda L. G. J., Kishi, Kasumi, Ellenbroek, Saskia I. J., Simons, Benjamin D., van Rheenen, Jacco, Hannezo, Edouard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382312/
https://www.ncbi.nlm.nih.gov/pubmed/32611816
http://dx.doi.org/10.1073/pnas.1921205117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382312/
https://www.ncbi.nlm.nih.gov/pubmed/32611816
http://dx.doi.org/10.1073/pnas.1921205117

Ejemplares similares